Natural Stacks Review: My Honest Opinion

Desk of Contents[Hide][Show]

Nootropics dietary supplements have been gaining extra reputation in recent times. Particularly with the elevated curiosity within the mind and biohacking. Since they’ve change into so common, there are actually lots of manufacturers on the market, however they’re not all created equal.

Pure Stacks is one nootropics model that I wished to check out. I attempted a couple of of their merchandise and wished to share some trustworthy ideas about how they affected me. However first, let’s cowl the fundamentals of nootropics.

What Are Nootropics and Why Use Them? 

Nootropics (additionally “sensible medicine” or cognitive enhancers) are substances that have an effect on the mind indirectly. They could defend the mind or improve cognitive efficiency. Nootropics may also enhance the effectivity of neurotransmitter manufacturing and the way they act on mind cells. 

What Is Pure Stacks?

Pure Stacks is a top quality complement firm that focuses on higher mind well being. The concept is to “stack” your dietary supplements so that you’ve one thing personalized to your wants. As a substitute of making an attempt to get every thing we want multi function complement (which isn’t going to occur).

You may get their pre-bundled stacks for particular well being wants, like temper, mind meals, and psychological efficiency, or create your personal bundle of dietary supplements. They provide merchandise individually, however stacking them will get you the perfect low cost. Extra on that on the finish of this evaluate, however for now let me inform you how Pure Stacks labored for me.

NEUROFUEL™ by Pure Stacks 

NEUROFUEL™ is Pure Stacks’ unique complement. It was initially known as CILTEP, an acronym for “Chemically-Induced Lengthy Time period Potentiation.” Don’t let the title idiot you although! Pure Stacks is made with all-natural components. 

The “chemically-induced” half refers to the way it will increase biochemical capabilities within the mind. Neurofuel does this by means of a couple of completely different actions:

  1. Inhibiting PDE enzymes
  2. Growing cAMP ranges

#1 Inhibiting Phosphodiesterase (PDE) Enzymes 

PDE enzymes would in any other case break down one thing known as cyclic adenosine monophosphate (cAMP). Blocking PDEs has a optimistic impact on reminiscence. Blocking PDE4, particularly, is useful for neurodegenerative ailments like Alzheimer’s and Parkinson’s. It could possibly additionally enhance wakefulness and focus. Some pure PDE4 inhibitors embody Artichoke extract, luteolin, and an herb known as Kanna. 

#2 Growing cAMP Ranges (Cyclic adenosine monophosphate)

cAMP naturally amps up the actions of hormones and neurotransmitters. These embody epinephrine (adrenalin) and acetylcholine. Whereas blocking PDE helps enhance cAMP ranges, Neurostack’s components additionally immediately enhance them. That is due to the herb, Coleus forskohlii, with its energetic compound, forskolin. Neurofuel makes use of artichoke extract to additionally assist block PDE. 

By blocking PDE and rising cAMP, it has a robust impact on a course of often called Lengthy Time period Potentiation. Scientists imagine this course of is the important thing to studying and retaining new info. 

Neurofuel additionally accommodates an amino acid, acetyl-L-carnitine (ALCAR). This amino acid crosses the blood-brain barrier to assist mitochondria and increase vitality. ALCAR additionally helps struggle mind fog and fatigue.

The L-phenylalanine within the method helps construct dopamine for focus and motivation. And the energetic type of vitamin B6 lowers emotions of stress and helps create calm, targeted vitality. You possibly can see why Neurofuel is so efficient for readability, focus, reminiscence, and motivation! 

My Expertise With NEUROFUEL™

I bought to strive each their capsule and their lemonade drink packets. I may really feel each merchandise inside half an hour. Regardless of a couple of brief nights of sleep, after taking Neurofuel, I felt targeted, clear-headed, and able to be productive. It was an incredible technique to begin the day. 

I particularly favored the lemonade packets as a result of it’s a good way to ensure I begin the day with a glass of water on an empty abdomen. They combine simply with out settling to the underside of the glass they usually style nice! 

The flavour comes from crystallized lemon extract, with some stevia and natural monk fruit for sweetness. No humorous enterprise right here. 


 Serotonin (aka the “comfortable molecule”) is a neurotransmitter that helps us really feel calm, targeted, and optimistic. Scientists have discovered that 95% of the physique’s serotonin is produced within the intestine. Once we feed our physique the proper vitamins, we will enhance serotonin manufacturing within the intestine. 

Pure Stacks’ Serotonin Mind Meals has the vitamins wanted for optimum serotonin manufacturing.

  • Rhodiola Rosea – Helps stress aid, combats fatigue and burnout, uplifts temper, and boosts vitality and efficiency.
  • L-Tryptophan – A vital amino acid that enhances temper, improves cognitive talents, and promotes optimistic behaviors. The intestine converts tryptophan to serotonin.
  • Vitamin B3 – Will increase blood stream within the mind, helps produce vitality, and protects the physique towards free radical injury. 
  • Magnesium Glycinate – Helps relieve stress, improves consideration, upgrades sleep high quality, and sharpens reminiscence.
  • Zinc Glycinate – Helps a wholesome immune system, and helps enhance serotonin within the mind. 

Wholesome serotonin ranges are linked with:

  • Optimistic social habits
  • Resilience within the face of stress
  • Optimism
  • Humor
  • Cognitive flexibility
  • Higher psychological well being on the whole

My Expertise With Pure Stacks’ Serotonin Mind Meals™ Complement

I took the serotonin complement largely within the night, but additionally in the course of the day on some overcast days. I may positively really feel an impact; typically, a way of balanced calm and a greater outlook. I believe it helped me sleep somewhat higher after I took it within the night. 

SMART CAFFEINE® by Pure Stacks

Generally you simply want somewhat further hit of caffeine… however with out the jitters. Pure Stacks’ Good Caffeine combines caffeine with the calming amino acid, L-theanine for a balanced vitality increase. L-theanine is the balancing amino acid discovered that comes from inexperienced tea. 

The 2 work collectively to enhance consideration and application, reminiscence, and cognitive functioning. It even helps us have the power to disregard distractions. What mama doesn’t want that!

A 2008 examine discovered  L-theanine and caffeine labored synergistically to enhance pace and accuracy when multitasking. The mix additionally decreased examine individuals’ susceptibility to distraction throughout a reminiscence process. Collectively they assist enhance efficiency when we have to actually use our brainpower.

My Expertise With Pure Stacks’ Caffeine Complement

I may positively really feel the caffeine, and it didn’t take lengthy for it to kick in. I took it about mid-morning after I was sitting at my laptop computer, typing an article, and was starting to really feel a bit sleepy. It helped convey again my focus rapidly and I felt far more productive for the remainder of the day. To date, I’ve simply taken it as wanted.  

Pure Stacks as a Complete: My Opinion

General, I felt that Pure Stacks dietary supplements labored very successfully and fairly rapidly. They’re an amazing nootropics hack to have readily available after I have to focus and be productive. Particularly after an evening of less-than-optimal sleep. The Neurofuel and Good Caffeine pair properly to assist benefit from the day.

The Serotonin Mind Meals can be an amazing complement to have on the shelf for days whenever you’re simply “not feelin’ it.”

I like that their components are all-natural and backed by science. Whereas I attempted these three merchandise, they’ve others you may add to your stack or experiment with. They’ve a couple of different neurotransmitter-enhancing dietary supplements, together with: 

  • Acetylcholine Mind Meals – For higher consideration to element, sooner pondering, and psychological readability. 
  • GABA Mind Meals – For a relaxed thoughts, clear ideas, relaxed physique, and deeper, extra restorative sleep.
  • Dopamine Mind Meals – For laser focus, unbeatable drive to get issues finished, higher athletic steadiness, and higher psychological readability.

In addition they have magnesium, curcumin, krill oil, probiotics, and Vitamin D3  dietary supplements. There’s even a drink combine to help sleep and intestine well being suddenly. In the event you’re undecided what to strive first, you may order one in every of their stacks, which mix two to 4 dietary supplements in a equipment. 

They even help you construct your personal stack. Simply select a product from every of three classes: Neurotransmitter Help, Psychological Efficiency, and Day by day Necessities. That can mechanically get you 15% off of the gathering.

I’m trying ahead to making an attempt extra of their merchandise! In the event you’d like to present Pure Stacks a strive at a 15% low cost, click on right here to go to their web site after which put in wellnessmama15 at checkout. 

Have you ever tried nootropics merchandise earlier than? What was your expertise with them? Share with us beneath!


  1. Hayashi Y. (2022). Molecular mechanism of hippocampal long-term potentiation – In direction of multiscale understanding of studying and reminiscence. Neuroscience analysis, 175, 3–15. 
  2. Levenson C. W. (2006). Zinc: the brand new antidepressant?. Diet opinions, 64(1), 39–42.
  3. Lou H. C. (1994). Dopamine precursors and mind operate in phenylalanine hydroxylase deficiency. Acta paediatrica (Oslo, Norway : 1992). Complement, 407, 86–88. 
  4. Owen, G. N., Parnell, H., De Bruin, E. A., & Rycroft, J. A. (2008). The mixed results of L-theanine and caffeine on cognitive efficiency and temper. Dietary neuroscience, 11(4), 193–198.
  5. Richard, D. M., Dawes, M. A., Mathias, C. W., Acheson, A., Hill-Kapturczak, N., & Dougherty, D. M. (2009). L-Tryptophan: Primary Metabolic Capabilities, Behavioral Analysis and Therapeutic Indications. Worldwide journal of tryptophan analysis : IJTR, 2, 45–60.
  6. Sanders, O., & Rajagopal, L. (2020). Phosphodiesterase Inhibitors for Alzheimer’s Illness: A Systematic Overview of Scientific Trials and Epidemiology with a Mechanistic Rationale. Journal of Alzheimer’s illness stories, 4(1), 185–215. 
  7. Southwick, S. M., Vythilingam, M., & Charney, D. S. (2005). The psychobiology of despair and resilience to emphasize: implications for prevention and remedy. Annual evaluate of scientific psychology, 1, 255–291.
  8. Tang, L., Huang, C., Zhong, J., He, J., Guo, J., Liu, M., Xu, J. P., Wang, H. T., & Zhou, Z. Z. (2019). Discovery of arylbenzylamines as PDE4 inhibitors with potential neuroprotective impact. European journal of medicinal chemistry, 168, 221–231.